Prodexin is a nonsteroidal anti-inflammatory drug. Prodexin works by reducing hormones that cause inflammation and pain in the body. Prodexin is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. Prodexin may also be used for purposes not listed in Prodexin guide.
Prodexin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Prodexin and call your doctor at once if you have:
chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
black, bloody, or tarry stools;
coughing up blood or vomit that looks like coffee grounds;
swelling or rapid weight gain, little or no urinating;
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
bruising, severe tingling, numbness, pain, muscle weakness;
fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions) or
severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
upset stomach, mild heartburn or stomach pain, diarrhea, constipation;
bloating, gas;
dizziness, headache, nervousness;
skin itching or rash;
blurred vision; or
ringing in your ears.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Side effects (in more detail)
Prodexin dosing
Usual Adult Dose for Ankylosing Spondylitis:
Initial: 250 mg to 500 mg or 275 mg to 550 mg (naproxen sodium) orally twice a day. The initial dose for Prodexin sodium controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day. Maintenance: May be increased to a daily maximum of 1500 mg (naproxen) or 1650 mg (naproxen sodium) in 2 divided doses, for limited periods up to 6 months. In patients who tolerate lower doses well, the dose of Prodexin sodium controlled-release may be increased to two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) orally once a day for limited periods.
Usual Adult Dose for Osteoarthritis:
Initial: 250 mg to 500 mg (naproxen) or 275 mg to 550 mg (naproxen sodium) orally twice a day. The initial dose for Prodexin sodium controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day. Maintenance: May be increased to a daily maximum of 1500 mg (naproxen) or 1650 mg (naproxen sodium) in 2 divided doses, for limited periods up to 6 months. In patients who tolerate lower doses well, the dose of Prodexin sodium controlled-release may be increased to two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) orally once a day for limited periods.
Usual Adult Dose for Rheumatoid Arthritis:
Initial: 250 mg to 500 mg or 275 mg to 550 mg (naproxen sodium) orally twice a day. The initial dose for Prodexin sodium controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day. Maintenance: May be increased to a daily maximum of 1500 mg (naproxen) or 1650 mg (naproxen sodium) in 2 divided doses, for limited periods up to 6 months. In patients who tolerate lower doses well, the dose of Prodexin sodium controlled-release may be increased to two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) orally once a day for limited periods.
Usual Adult Dose for Acute Gout:
750 mg (naproxen) or 825 mg (naproxen sodium) orally one time, followed by 250 mg (naproxen) or 275 mg (naproxen sodium) every 8 hours until the gouty attack has resolved, usually 2 to 3 days. The recommended dose of Prodexin sodium controlled-release is two to three 500 mg tablets (1000 to 1500 mg) orally on the first day, followed by two 500 mg tablets (1000 mg) orally daily until the attack has subsided.
Usual Adult Dose for Bursitis:
550 mg Prodexin sodium orally once, followed by 550 mg Prodexin sodium every 12 hours, or 275 mg /250 mg (naproxen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Prodexin sodium or 1000 mg Prodexin. The recommended initial dose of Prodexin sodium controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).
Usual Adult Dose for Tendonitis:
550 mg Prodexin sodium orally once, followed by 550 mg Prodexin sodium every 12 hours, or 275 mg (naproxen sodium)/250 mg (naproxen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Prodexin sodium or 1000 mg Prodexin. The recommended initial dose of Prodexin sodium controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).
Usual Adult Dose for Dysmenorrhea:
550 mg Prodexin sodium orally once, followed by 550 mg Prodexin sodium every 12 hours, or 275 mg /250 mg (naproxen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Prodexin sodium or 1000 mg Prodexin. Over-the-counter preparation: Prodexin sodium 220 mg orally every 8 hours as needed. Do not exceed 2 caplets in any 8- to 12-hour period. The recommended initial dose of Prodexin sodium controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).
Usual Adult Dose for Pain:
550 mg Prodexin sodium orally once, followed by 550 mg Prodexin sodium every 12 hours, or 275 mg (naproxen sodium)/250 mg (naproxen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Prodexin sodium or 1000 mg Prodexin. Over-the-counter preparation: Prodexin sodium 220 mg orally every 8 hours as needed. Do not exceed 2 caplets in any 8- to 12-hour period. The recommended initial dose of Prodexin sodium controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).
Usual Geriatric Dose for Pain:
Over-the-counter preparation - 220 mg orally every 12 hours or 250 mg (naproxen) orally every 8 hours as needed.
Usual Pediatric Dose for Fever:
Dosage guidelines are based on Prodexin: Greater than 2 years: 2.5 to 10 mg/kg/dose. Maximum daily dose is 10 mg/kg, given every 8 to 12 hours.
Usual Pediatric Dose for Pain:
Dosage guidelines are based on Prodexin: Greater than 2 years: 2.5 to 10 mg/kg/dose. Maximum daily dose is 10 mg/kg, given every 8 to 12 hours.
Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:
Dosage guidelines are based on Prodexin: Greater than or equal to 2 years: 5 mg/kg orally twice a day. Maximum dose: 1000 mg/day.
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References
Dailymed."Naproxen: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Prodexin be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
How should I take Prodexin?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
The delayed-release tablet is a slower-acting form of Prodexin and should be used only for treating arthritis or ankylosing spondylitis. Follow your doctor's instructions.
Do not crush, chew, or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. The enteric-coated pill has a special coating to protect your stomach.
Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
If you use this medication long-term, you may need frequent medical tests at your doctor's office.
Store at room temperature away from moisture and heat.
Who should not take Prodexin?
Prodexin may increase your risk of heart attack or stroke, especially if you use it long term or have heart disease. Do not use this medicine just before or after heart bypass surgery.
Prodexin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking Prodexin.
You should not use Prodexin if you are allergic to it, or if you have a history of allergic reaction to aspirin or other NSAIDs.
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:
a history of heart attack, stroke, or blood clot;
heart disease, congestive heart failure, high blood pressure;
a history of stomach ulcers or bleeding;
liver or kidney disease;
asthma;
polyps in your nose;
a bleeding or blood clotting disorder; or
if you smoke.
FDA pregnancy category C. Before using Prodexin, tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking Prodexin during the last 3 months of pregnancy may result in birth defects. Do not take Prodexin during pregnancy unless your doctor has told you to.
Prodexin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not give this medicine to a child younger than 2 years old without medical advice.
What other drugs will affect Prodexin?
Ask your doctor before using Prodexin if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.
Ask a doctor or pharmacist if it is safe for you to use Prodexin if you are also using any of the following drugs:
a blood thinner (warfarin, Coumadin);
lithium;
methotrexate;
a diuretic or "water pill";
steroids (prednisone and others);
aspirin or other NSAIDs--ibuprofen (Advil, Motrin), celecoxib, diclofenac, indomethacin, meloxicam, and others; or
heart or blood pressure medication--benazepril, candesartan, enalapril, lisinopril, losartan, olmesartan, quinapril, ramipril, telmisartan, valsartan, and others.
This list is not complete. Other drugs may interact with Prodexin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Can Prodexin be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Prodexin be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
Reviews
Following the study conducted by gmedication.com on Prodexin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Prodexin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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